CLINICAL-ASSESSMENT OF ANTIDEPRESSIVE ACT IVITY OF FLUOXETINE

The authors studied therapeutic properties of fluoxetine in the treatm ent of 100 patients with endogenous depressions. the drug was introduc ed during 6 weeks in a daily dose 20 mg. On the basis of the analysis of its clinical action and adverse reactions, fluoxetine belonging to the class of antidepressants has been ascertained. A prevalence of thy moleptical and stimulating components in its action, equal by their de gree of expressivity and a smaller degree of anxiolytical effect have been demonstrated. Differentiated indications to fluoxetine prescripti on, its prediction in the therapy of apatho-adynamical and melancholic depressions and the feasibility of its use in inpatient conditions ar e discussed.