PROGNOSTIC IMPLICATION OF HELICOBACTER-PY LORI IDENTIFICATION IN ULCER PATIENTS

The author shows that persistent contamination of the mucosa in ulcer patients noticeable even after ulcer healing with Helicobacter pylori leads to disordered coordination of enegretic processes in immunocompe tent cells. The reserve pathway becomes more active than basic pathway of oxidation, this combining with lymphocyte sensitization to the muc osal tissue. An unfavourable prognostic implication is given to a 1.5- fold inhibition of lymphocyte succinate dehydrogenase activity, If alp ha-glycerophosphate dehydrogenase is 2.3 times higher than normal and leukocyte migration index is under 0.65, the prognosis is also likely to be unfavourable.