STIMULATING EFFECT OF FORIDON, A CALCIUM- ANTAGONIST, ON ABSORPTION FOUND AT SEGMENTAL PERFUSION OF THE SMALL-INTESTINE

Authors
PARFENOV AI FAZYLOV AV POLEVA NI
Citation
Ai. Parfenov et al., STIMULATING EFFECT OF FORIDON, A CALCIUM- ANTAGONIST, ON ABSORPTION FOUND AT SEGMENTAL PERFUSION OF THE SMALL-INTESTINE, Kliniceskaa medicina, 72(6), 1994, pp. 42-44
Citations number
23
Categorie Soggetti
Medicine, General & Internal
Journal title
Kliniceskaa medicina → ACNP
ISSN journal
00232149
Volume
72
Issue
6
Year of publication
1994
Pages
42 - 44
Database
ISI
SICI code
0023-2149(1994)72:6<42:SEOFAC>2.0.ZU;2-4
Abstract
A continuous perfusion of the jejunal segment has been performed in 18 patients with chronic intestinal diseases. The addition of 40 mg fori don, a calcium antagonist from dihydropyridine series increased the ab sorption rate of glucose, Na+ and water by 28.0%, 44.3% and 41.1%, res pectively. The stimulating effect was independent of basal absorption and did not impair the absorption. It is planned to test foridon and o ther calcium antagonists as antidiarrheal medication.