Our experience with 18 patients with simple epidermoid cysts of the te
stis (monodermal teratoma) is reported. In all patients the tumor was
enucleated completely and 2 biopsies of the adjacent parenchyma were o
btained for exclusion of associated germ cell cancer, scar or carcinom
a in situ. There was no evidence of malignancy in any biopsy specimen.
Preoperative evaluation included physical examination, testicular son
ography, and determination of cu-fetoprotein and beta-human chorionic
gonadotropin levels. Although epidermoid cyst was strongly suggested b
y sonography, the ultrasonic appearance was not specific and inguinal
testicular exploration was required. In 1 patient multiple epidermoid
cysts of the right testis were associated with an adult teratoma conta
ining embryonal carcinoma and choriocarcinoma of the left testicle. To
our knowledge no similar case has been described in the literature. B
ased on our results and our experience, we consider tumor enucleation
and biopsy of the adjacent parenchyma as adequate treatment for the be
nign epidermoid cyst. The literature concerning organ sparing surgery
in testicular epidermoid cysts is reviewed.