The frequency and timing of the delayed appearance of sperm following
an end-to-side vasoepididymostomy were determined in 89 patients. The
surgical patency rate, defined as greater than 1 million sperm in the
ejaculate, was 56% (50 of 89 consecutive patients). None of the 7 pati
ents without sperm in the epididymal fluid at the anastomosis had sper
m in the ejaculate postoperatively. Of the remaining 82 patients 31 ha
d sperm on initial semen analysis within 3 months postoperatively. Sev
en of the 51 patients whose initial postoperative semen sample reveale
d azoospermia were lost to followup. Among the remaining 44 patients 1
8 (41%) had delayed appearance of sperm in the ejaculate (mean delay 6
months, range 3 to 15). The ultimate mean sperm count and motility in
the patients with initially positive postoperative semen samples were
not significantly different from those in patients with delayed appea
rance of sperm. In addition, the delayed anastomotic obstruction for b
oth groups was the same (10% and 11%, respectively). Our results demon
strate that delayed appearance of sperm after end-to-side vasoepididym
ostomy is common and that the prognosis for patients with delayed appe
arance of sperm is not significantly worse than that for patients with
sperm on the initial semen analysis.