Mj. Chehval et al., THE EFFECT OF UNILATERAL INJURY TO THE VAS-DEFERENS ON THE CONTRALATERAL TESTIS IN IMMATURE AND ADULT-RATS, The Journal of urology, 153(4), 1995, pp. 1313-1315
The relationship between alterations in testicular histology and antis
perm antibodies in immature and mature Lewis rats subjected to unilate
ral vasectomy was studied. Forty percent of immature rats and 90% of m
ature rats (p < 0.01) demonstrated significant alterations in both the
obstructed (vasectomy) testis and the contralateral testis. There wer
e significant changes in antisperm antibodies (ELISA) in the animals w
hich demonstrated histologic changes.