CANDIDOSIS OF THE URINARY-TRACT WITH PADDING PHENOMENON OF THE RENAL PELVISES IN AN INFANT WITH OBSTRUCTIVE UROPATHY

A male infant with obstructive uropathy developed yeast cell agglomera tions which were detectable macroscopically and by image-generating te chniques within both renal pelvises after Candida albicans infection o f the urinary tract. Therapy with flucytosine induced excretion of 'fu ngal balls' via the urethra. Continuation of therapy with liposomal am photericin B (AmBisome(R)) prevented a relapse after development of fu ngal resistance against flucytosine. Sonographically or radiographical ly detectable formation of 'concrements' within the urinary tract of p atients with an immature or compromised immune system and additional f eatures such as obstructive urinary tract should suggest a localized o r systemic mycosis, particularly in the context of long-term antibioti c treatment.