C. Hamanishi et al., BONE-MINERAL DENSITY CHANGES IN DISTRACTED CALLUS STIMULATED BY PULSED DIRECT ELECTRICAL-CURRENT, Clinical orthopaedics and related research, (312), 1995, pp. 247-252
To evaluate the effect of application of pulsed direct current electri
cal stimulation to callus tissue, a l-cm bone-lengthening model using
an external lengthener was applied to rabbit tibia, Twenty-microampere
pulsed direct current was applied 12 hours daily from the day of oste
otomy until 40 days after the completion of lengthening, The area, bon
e mineral content, and bone mineral density of the distracted callus a
nd of the proximal and distal segments of the tibia were evaluated usi
ng dual-energy xray absorptiometry. The absolute and relative values o
f bone mineral density of the electrically stimulated callus were sign
ificantly increased as compared with those in the control group, Pulse
d direct current electrical stimulation may be indicated in bone lengt
hening to stimulate the poorly mineralized callus, and may shorten the
overall time course of leg lengthening.