Ak. Salama et Ma. Radwan, UPTAKE, EXCRETION, AND METABOLISM OF PHORATE IN THE LAND SNAIL, HELIX-ASPERSA (MULLER), Journal of environmental science and health. Part B. Pesticides, food contaminants, and agricultural wastes, 30(2), 1995, pp. 233-242
Uptake, excretion, and metabolism of phorate (O,O-diethyl S-ethyltkiom
ethyl phosphorodithioate) following application to lettuce leaves were
investigated in the land snail, Helix aspersa. Snails were fed on a l
eaf disc of lettuce immersed in a solution of 100 ppm of phorate. Snai
ls were dissected at time intervals between 1 and 7 days after dosing.
Phorate was readily absorbed within 24 hrs following ingestion. The a
mount of phorate reached a peak value of 880 mu g at 4 days, and then
dropped as time passed to the end of experiment (7 days) indicating th
ere was no accumulation of the compound in the snail tissues. Phorate
was metabolized to phorate sulfoxide and phorate sulfone. Phorate and/
or its metabolites were rapidly excreted soon after ingestion. The maj
or compound identified in the excreta was the unchanged phorate.