Eighty-five children and 230 adults from a population study performed
ambulatory peak now readings three times a day for 1 to 2 weeks follow
ing a home visit. Three peak expiratory flow (PEF) readings were repor
ted for each of 5,809 test sessions. Within each test session, the thi
rd maneuver most frequently (40% of the time) gave the highest PEF rea
ding. This did not vary throughout the day. In subgroups of children a
nd women with a history of asthma or asthma symptoms (hereinafter refe
rred to as ''asthma''), the first maneuver during the evening test ses
sions more frequently gave the highest readings. However, maneuver-ind
uced bronchospasm occurred during less than 5% of the test sessions in
both subjects with asthma and in other subjects. The within test sess
ion PEF reproducibility was good: overall, the highest and second high
est reading matched within one division (10 L/min) 73% of the time and
within 30 L/min (9% of the reading) 95% of the time. The best reprodu
cibility was noted after the first two days of testing, during evening
and bedtime test sessions (vs morning), and in girls and men. In the
group with at least 2 weeks of testing, the coefficient of repeatabili
ty (CR) for the week-to-week PEF lability index was 10% for healthy ad
ults and 17% for healthy children. As expected, repeatability was not
as good for adults with asthma (CR = 17%) and children with asthma (CR
= 28%).