ADMINISTRATION OF GRANULOCYTE-COLONY-STIMULATING FACTOR TO NEUTROPENIC LOW-BIRTH-WEIGHT INFANTS OF MOTHERS WITH PREECLAMPSIA

Nine low birth weight infants with neutropenia born to mothers with pr eeclampsia were treated with granulocyte-colony stimulating factor, 10 mu g/kg intravenously, within 24 hours of birth and at 24-hour interv als for a maximum of three doses if neutropenia persisted. the absolut e neutrophil count increased significantly in eight of the nine infant s within 6 hours, and neutrophilia was sustained for at least 72 hours after administration of a single dose of granulocyte-colony stimulati ng factor.