DERMATOPATHIC LYMPHADENOPATHY FOLLOWING A DRUG-INDUCED HYPERSENSITIVITY - CYTOLOGICAL, IMMUNOCYTO AND IMUNOSHITOLOGICAL, ULTRASTRUCTURAL ASPECT - ONE CASE

In addition to the morphological details obtained from the imprints, a simple immunocytological study allowed us to diagnose one case of a d ermopathic lymphadenopathy simulating a T cell lymphoma, following a d rug-induced erythrodermia. We were able to identify the increase of CD 1a+ and Prot. S100+ cells on acetone fixed imprints. The histological, immunohistological and ultrastructural investigations confirmed the v alue of the cytological study and that the dendritic cells were Langer hans cells (Birbeck granules+). Most of them were considered as migrat ing from the dermal lesions.