Urethral prolapse is a benign lesion of the terminal urethra, usually
seen in young Negroid girls. Twenty-seven children with urethral prola
pse treated at the University Hospital of the West Indies between Janu
ary 1982 and December 1991 were prospectively studied; 74% were betwee
n the ages of 3 and 7 years. Bloody discharge was the most common symp
tom. Vulval bleeding together with a bruised appearance of the urethra
resulted in erroneous initial suspicion of sexual abuse in 3 children
. Prolapse was graded from I to IV depending on the extent of prolapse
and degree of inflammation. Initial therapy in the 25 prepubertal gir
ls consisted of sitz baths and topical application of either an antimi
crobial ointment (15 girls) or 0.5% oestrogen cream (10), chosen rando
mly. Complete resolution of the prolapse occurred in only 4 children,
3 of them from the oestrogen group. Although the oestrogen led to a be
tter response, it also caused theliarchy in 2 girls. Three children wh
o had only transient improvement and 2 post-pubertal patients had surg
ical excision of the prolapse. Post-excision there were no complicatio
ns or recurrence of prolapse. Three girls who had improvement with non
operative therapy continued to have grade II prolapse even after puber
ty. Initial therapy of urethral prolapse in prepubertal girls can be n
on-surgical, however, when this fails to achieve resolution surgical e
xcision is simple, safe, and curative.