We examined 55 SLE patients. By the treatment the patients entered 5 g
roups: groups I and IT received gammaferon plus reaferon, groups III a
nd IV received IFN plus cyclophosphamide and control group V received
placvenil. Compared to controls, the best results were obtained tn pat
ients on gammaferon combined with cyclophosphamide. IFN preparations a
lone showed less pronounced effects. No changes were registered in the
control group. We believe that IFN preparations demonstrated efficacy
against SLE.