An Al body target with improved yields of electrophilic [F-18]F-2 on t
he Siemens/CTI 11 MeV proton cyclotron at Wisconsin has been developed
. The saturation yield is 3.10 +/- 0.40 GBq/mu A for beam currents up
to 45 mu A. The target has routinely produced 20-40 GBq of [F-18]F-2 f
or clinical and experimental use over 1600 mu A-h operation, with a ma
ximum yield to date of 45.5 GBq (1.2 Ci). Target design, performance a
nd reliability are discussed.