Jp. Lesbre et M. Peltier, A RAPIDLY GROWING VALVULAR HEART-DISEASE - DEGENERATIVE AORTIC-STENOSIS - DIAGNOSTIC AND THERAPEUTIC ELEMENTS, Annales de cardiologie et d'angeiologie, 44(1), 1995, pp. 41-45
Ostial aortic stenosis is clearly the commonest form of valvular heart
disease in adults at the present time, as it represents 26% of all fo
rms of valvular heart disease and 2% of all forms of heart disease. It
is a disease middle and old-age, which appears to becoming increasing
ly frequent due to ageing of the population. It affects men twice as o
ften as women and sometimes has a misleading clinical presentation at
the stage of heart failure due to disappearance of the usual systolic
murmur. The patient may simply present with signs of refractory left v
entricular failure or complete heart failure. The diagnosis and follow
-up have been radically transformed by the development of Doppler ultr
asonography which allows the positive diagnosis as well as a very prec
ise assessment of the severity, avoiding the need for cardiac catheter
ization, but unfortunately coronary angiography still remains essentia
l in view of the age of these patients. In terms of treatment, percuta
neous valvuloplasty according to the method developed by Cribier has u
nfortunately not lived up to expectations and tight aortic stenosis re
mains a surgical disease whose results are among the most spectacular:
the patient's dramatic functional and objective transformation follow
ing insertion of a valvular prosthesis (mechanical before the age of 7
5 years, bioprosthesis after this age), at the cost of a reasonable op
erative mortality of approximately 5 to 8% in the 71 to 80 year age-gr
oup, must be stressed.