NUCLEOTIDE AND PREDICTED PEPTIDE SEQUENCE OF FELINE INTERFERON-GAMMA (IFN-GAMMA)

Authors
ARGYLE DJ SMITH K MCBRIDE K FULTON R ONIONS DE
Citation
Dj. Argyle et al., NUCLEOTIDE AND PREDICTED PEPTIDE SEQUENCE OF FELINE INTERFERON-GAMMA (IFN-GAMMA), DNA sequence, 5(3), 1995, pp. 169-171
Citations number
11
Categorie Soggetti
Biothechnology & Applied Migrobiology","Genetics & Heredity
Journal title
DNA sequence → ACNP
ISSN journal
10425179
Volume
5
Issue
3
Year of publication
1995
Pages
169 - 171
Database
ISI
SICI code
1042-5179(1995)5:3<169:NAPPSO>2.0.ZU;2-8
Abstract
Interferon gamma is a pleiotropic cytokine which is now recognised as an important modulator of the immune response. We now report the cloni ng and sequencing of feline interferon gamma cDNA which was generated by the polymerase chain reaction. At the nucleotide level feline ifn-g amma shares 78% and 63% homology with human and murine cDNA equivalent s. At the amino acid level the feline IFN-gamma shares 63% and 43% hom ology with human and murine homologs respectively.