EVALUATION OF THE POLAROGRAPHIC TECHNIQUE FOR ASSAY OF THE VIABILITY OF FREEZE-DRIED BCG VACCINE .1. THE POLAROGRAPHIC TECHNIQUE

Authors
MALUCELLI MIC NIERO R LUCCHIARI PH BACILA M
Citation
Mic. Malucelli et al., EVALUATION OF THE POLAROGRAPHIC TECHNIQUE FOR ASSAY OF THE VIABILITY OF FREEZE-DRIED BCG VACCINE .1. THE POLAROGRAPHIC TECHNIQUE, Vaccine, 13(3), 1995, pp. 268-272
Citations number
15
Categorie Soggetti
Immunology
Journal title
Vaccine → ACNP
ISSN journal
0264410X
Volume
13
Issue
3
Year of publication
1995
Pages
268 - 272
Database
ISI
SICI code
0264-410X(1995)13:3<268:EOTPTF>2.0.ZU;2-C
Abstract
In this paper, a new assay based on oxygen uptake assessed by polarogr aphy was evaluated with the aim of establishing the viability of freez e-dried BCG vaccine. An oxygen electrode possessing a temperature sens or was designed for this purpose. The polarographic method used had se veral advantages, particularly its rapidity and use of small amounts o f biological material. These advantages are ideal for quality control of BCG vaccine.