Nevus Ota is a disfiguring facial dermal melanosis that is observed ra
rely in Caucasians but is common in Asians. Until recently, carbon dio
xide snow cryotherapy had been used most frequently to treat this diso
rder, but the results were not always satisfactory and often left scar
ring after treatment. During the past 15 years, we have treated a tota
l of 600 cases of dermal pigmentary facial disfiguration using CRYO-MI
NI, a liquid nitrogen cryogenic instrument with a removable disk-shape
d copper tip. We have found this method to be simple and extremely eff
ective in the treatment of nevus Ota and senile lentigines, and it is
also useful for treatment of delayed nevus spilus and blue nevus. This
report presents our techniques and experiences as well as the results
achieved with four patients who have a deeply situated type of nevus
Ota. Associated problems to be considered in future treatment are disc
ussed also.