To determine the applicability of the nonreversed vein graft technique
to 1-mm-diameter vessels, 24 New Zealand White rabbits underwent bila
teral replacement of 2-cm defects in the femoral artery with vein graf
t conduits. On one side a standard reversed vein graft (RVG) was emplo
yed, and on the other side a nonreversed vein graft (NRVG) was placed
after valve disruption with a Hall valvulotome. Patency rates were not
statistically different (RVG 87 percent, NRVG 96 percent, p > 0.1). E
lectron and light microscopy revealed similar endothelial damage and t
ime to endothelial recovery between the two techniques. There was no d
ifference in flow volume between the two techniques. We conclude that
the NRVG technique has acceptable patency rates in 1-mm-diameter vesse
ls within the parameters of this study but that further research is re
quired to determine clinical applicability.