A series of 27 transtracheal needle aspiration biopsies performed on 2
5 patients were reviewed. A rigid bronchoscope and rigid needle were u
sed. The biopsies were performed as staging procedures in patients wit
h bronchogenic carcinoma, or to obtain diagnoses in patients with medi
astinal adenopathy. A cytopathologist attended 11 biopsies and microsc
opically examined a direct smear to determine adequacy. Repeat biopsie
s were taken at the time if necessary. A diagnosis was obtained in 9/1
1 (81%) of these cases. Only 3/16 biopsies (18.8%) performed in the ab
sence of a pathologist were diagnostic. All negative cases were subseq
uently found to have disease (2 sarcoidosis, 13 cancer) by other metho
ds including mediastinoscopy in 5 cases. In the patient group sampled,
the technique of rigid needle and rigid bronchoscope with a cytopatho
logist in attendance resulted in a much higher sensitivity for the tes
t than has been previously reported. (C) 1995 Wiley-Liss, Inc.