SYNTHESIS OF SEGMENT-C OF TAUTOMYCIN

Authors
JIANG YM ICHIKAWA Y ISOBE M
Citation
Ym. Jiang et al., SYNTHESIS OF SEGMENT-C OF TAUTOMYCIN, Synlett, (3), 1995, pp. 285-288
Citations number
29
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
3
Year of publication
1995
Pages
285 - 288
Database
ISI
SICI code
0936-5214(1995):3<285:SOSOT>2.0.ZU;2-Z
Abstract
Synthesis of Segment C of tautomycin was accomplished from 2 D-sugar d erivatives. New heteroconjugate addition strategy allowed stereocontro lled syntheses of the 2 sub-segments, C-1 and C-2, and 3 other diaster eoisomers of the latter. Sub-segments were coupled between sulfone car banion and epoxide electrophile to furnish the spiro ring moiety of th e target compound.