WEAK FORCES IN THE THERMODYNAMIC STEREOSELECTIVITY OF PROTON AND COPPER(II) COMPLEXES WITH DIASTEREOISOMERIC DIPEPTIDES CONTAINING AROMATICSIDE-CHAINS

Authors
CUCINOTTA V GRASSO G MACCARRONE G MASTRUZZO L PAPPALARDO G
Citation
V. Cucinotta et al., WEAK FORCES IN THE THERMODYNAMIC STEREOSELECTIVITY OF PROTON AND COPPER(II) COMPLEXES WITH DIASTEREOISOMERIC DIPEPTIDES CONTAINING AROMATICSIDE-CHAINS, Inorganica Chimica Acta, 228(2), 1995, pp. 119-125
Citations number
32
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Inorganica Chimica Acta → ACNP
ISSN journal
00201693
Volume
228
Issue
2
Year of publication
1995
Pages
119 - 125
Database
ISI
SICI code
0020-1693(1995)228:2<119:WFITTS>2.0.ZU;2-O
Abstract
The origins of thermodynamic stereoselectivity in proton and copper(II ) complexes of diastereoisomeric dipeptides with aromatic side chains were investigated. The use of a combined approach (potentiometric and calorimetric measurements together with spectroscopic studies) made it possible to examine the different forces that drive stereoselectivity . The aromatic side chains seem to assist proton complex formation (in different ways) in comparison with copper(II) complexation. This diff erent role of side-chain residues is ascribed to a possible d-pi inter action existing in both the copper(II) complexes with the two diastere oisomeric dipeptides.