INTERPOSITION OF NARROW CYCLOPERISTALTIC SEGMENTS INTO ISOLATED SEGMENTS OF JEJUNUM - INFLUENCE ON FLUID PERFUSION

Two isolated segments of jejunum with the ends exteriorised as jejunos tomies were created in each of 8 dogs. Towards the end of one of the t wo, a cycloperistaltic (C-P) segment, with a diameter 70% of that of t he jejunum, was interposed. Fluid containing (14)polyethylene glycole was infused at 4 ml/min through each of the 16 preparations and the re sults were compared. The presence of a C-P segment significantly reduc ed the volume of output (with C-P segment - mean (+/- standard deviati on) 155,27 +/- 14,81 ml/h v. without C-P segment - 210,09 +/- 19,41 ml /h) (P < 0,001) and increased absorption (with C-P 45,44 +/- 20,86 ml/ h v. without C-P - 20,48 +/- 8,42 ml/h) (P < 0,001) and pooling (with C-P - 39,29 +/- 16,99 ml/h v. without C-P - 9,42 +/- 17,16 ml/h) (P < 0,001). The C-P segment therefore delayed the passage of the perfused fluid.