Mj. Renan et al., A PIXE STUDY OF ELEMENTAL CONCRETIONS IN AORTIC-WALL TISSUE, Journal of radioanalytical and nuclear chemistry, 199(4), 1995, pp. 277-287
Calcification of implanted biological heart valves leads to malfunctio
n after a certain period. The substance mainly responsible for accumul
ated calcium deposits in glutaraldehyde. The study was divided into wa
s phases: chemical detoxification of the tissue by glutaraldehyde extr
action to minimize calcification, and a subsequent PIXE analysis of mo
re than 80 aortic wall samples to examine the efficiency of the detoxi
fication process.