DNA DISCRIMINATION BY GAL4 AND OTHER C6 ZINC CLUSTER PROTEINS

Authors
Citation
M. Suzuki et N. Yagi, DNA DISCRIMINATION BY GAL4 AND OTHER C6 ZINC CLUSTER PROTEINS, Proceedings of the Japan Academy. Series B Physical and biological sciences, 71(2), 1995, pp. 87-91
Citations number
19
Categorie Soggetti
Multidisciplinary Sciences",Biology
ISSN journal
03862208
Volume
71
Issue
2
Year of publication
1995
Pages
87 - 91
Database
ISI
SICI code
0386-2208(1995)71:2<87:DDBGAO>2.0.ZU;2-A
Abstract
DNA discrimination by C6 zinc cluster proteins is discussed. Monomer p roteins in this family bind to the CGG sequence. We propose that C6 di mers bind to CGGN(n=10-12)CCG or CGGN(n=4-7)CCG depending on whether d imerisation takes place over the DNA minor groove or the DNA major gro ove at the centre of the binding site.