PURPOSE: To evaluate the safety and efficacy of biliary intervention p
erformed by means of percutaneous transjejunal access. MATERIALS AND M
ETHODS: In 28 patients with conventional antecolic Roux-en-Y choledoch
ojejunostomy or hepaticojejunostomy loops, 41 attempts were made at di
rect percutaneous entry into the jejunal loop. Indications for previou
s surgery included sclerosing cholangitis, orthotopic liver transplant
ation, cholangiocarcinoma, bypass of benign iatrogenic strictures, and
bypass of choledochal cyst. Roux-en-Y loops were directly accessed wi
th single-wall, 19-gauge needles after localization by review of previ
ous cholangiograms or computed tomographic (CT) scans and localization
of surgical clips with fluoroscopy. RESULTS: The transjejunal approac
h was successful in 36 of 41 attempts. In 30 cases, transhepatic punct
ure was entirely avoided. There were four minor complications and one
major complication of biliary sepsis. No procedure-related deaths occu
rred. CONCLUSION: This transjejunal approach is an effective and safe
route for a variety of percutaneous biliary procedures in patients wit
h biliary-enteric anastomoses.