MR-IMAGING OF INTRAHEPATIC CHOLANGIOCARCINOMA

Background: The purpose of this study was to determine the magnetic re sonance (MR) features of intrahepatic cholangiocarcinoma. Methods: MR imaging studies of seven cases of pathologically proven intrahepatic c holangiocarcinoma were retrospectively reviewed. Results: On MR images the tumors presented as a single mass (N = 5) or multiple nodules (N = 2), as well-delineated (N = 5) or ill-defined (N = 2), and as nonenc apsulated (N = 7). Mean tumor diameter ranged from 6-14 cm (mean, 10 c m). On T1-weighted (TR/TE = 400-600/10-17 msec) images, the tumors wer e hypointense compared to the liver. The five tumors studied with dyna mic MR imaging showed progressive centripetal filling-in after intrave nous administration of a gadolinium chelate. On T2-weighted (TR/TE = 2 000-2500/80-100 msec) images, all tumors were hyperintense compared to the liver; five were markedly hyperintense and two moderately hyperin tense. Vascular encasement, bile duct dilatation within the tumor, and central scar were depicted on MR images in four, three, and two tumor s respectively. Conclusion: The typical MR appearance of intrahepatic cholangiocarcinoma is a large well-delineated nonencapsulated tumor as sociated with intrahepatic venous encasement.