REACTIONS OF 3-ARYL-1-METHYL-1,3-DIKETONES WITH CYANOACETAMIDE CATALYZED BY LIPASE FROM CANDIDA-CYLINDRACEA .2.

Authors
MIJIN DZ MISICVUKOVIC MM
Citation
Dz. Mijin et Mm. Misicvukovic, REACTIONS OF 3-ARYL-1-METHYL-1,3-DIKETONES WITH CYANOACETAMIDE CATALYZED BY LIPASE FROM CANDIDA-CYLINDRACEA .2., Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 34(4), 1995, pp. 348-350
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
34
Issue
4
Year of publication
1995
Pages
348 - 350
Database
ISI
SICI code
0376-4699(1995)34:4<348:RO3WCC>2.0.ZU;2-9
Abstract
Lipase from Candida cylindracea has been used to synthesize 4,6-(methy l, aryl-disubstituted)-3-cyano-2-pyridones (2) by condensation of 3-ar yl-1-methyl-1,3-diketones (1) with cyanoacetamide in water at 40-degre es-C. Synthesis has been performed in an excess of cyanoacetamide and products have been characterized by IR and H-1 NMR spectroscopy.