Peritoneal dialysis adequacy in the narrowest sense of the world can b
e evaluated by several indexes. Residual kidney function and caloric p
rotein intake strongly affect the protein metabolism (creatinin, urea)
they reflect. The correlation between dialysis adequacy indexes and c
linical issue (survival, mortality and morbidity) is rather poor. Each
index sets the inferior security limit, but in no way a target to be
aimed at. Furthermore, the artificial organ should maintain a normal f
luid and electrolyte balance and blood pressure, as performed by the n
atural kidney. The posology indexes do not materialize this important
function. No single indicator can replace clinical evaluation and good
sense.