SYNTHESIS OF PRODRUGS AND A MUTUAL PRODRUG OF CHLORZOXAZONE AND ACETAMINOPHEN BASED ON A MASKED BENZOXAZOLONE

Authors
VIGROUX A BERGON M
Citation
A. Vigroux et M. Bergon, SYNTHESIS OF PRODRUGS AND A MUTUAL PRODRUG OF CHLORZOXAZONE AND ACETAMINOPHEN BASED ON A MASKED BENZOXAZOLONE, Bioorganic & medicinal chemistry letters, 5(5), 1995, pp. 427-430
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
5
Issue
5
Year of publication
1995
Pages
427 - 430
Database
ISI
SICI code
0960-894X(1995)5:5<427:SOPAAM>2.0.ZU;2-7
Abstract
A series of alkyl and aryl N-(5-chloro-2-hydroxyphenyl)carbamates, pro drugs of chlorzoxazone, have been synthesized. The synthesis in a five -step process of one of them, 4-acetamidophenyl ester, a mutual prodru g of chlorzoxazone and acetaminophen, is described.