A NOVEL BICYCLIC ORTHOESTER AS A CHIRAL AUXILIARY - APPLICATION TO THE SYNTHESIS OF ALPHA-HYDROXY ACIDS

Authors
DUBE D DESCHENES D TWEDDELL J GAGNON H CARLINI R
Citation
D. Dube et al., A NOVEL BICYCLIC ORTHOESTER AS A CHIRAL AUXILIARY - APPLICATION TO THE SYNTHESIS OF ALPHA-HYDROXY ACIDS, Tetrahedron letters, 36(11), 1995, pp. 1827-1830
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
11
Year of publication
1995
Pages
1827 - 1830
Database
ISI
SICI code
0040-4039(1995)36:11<1827:ANBOAA>2.0.ZU;2-S
Abstract
Chiral alpha-keto orthoesters derived from tartaric acid can be reduce d diastereoselectively. Hydrolysis affords optically active alpha-hydr oxy acids and the recovered auxiliary.