ALPHA,OMEGA-DIALKYL-SUBSTITUTED POLYENES BY PALLADINM-CATALYZED COUPLING REACTIONS OF VINYLTIN COMPOUNDS WITH VINYL HALIDES

Authors
KIEHL A EBERHARDT A MULLEN K
Citation
A. Kiehl et al., ALPHA,OMEGA-DIALKYL-SUBSTITUTED POLYENES BY PALLADINM-CATALYZED COUPLING REACTIONS OF VINYLTIN COMPOUNDS WITH VINYL HALIDES, Liebigs Annalen, (2), 1995, pp. 223-230
Citations number
41
Categorie Soggetti
Chemistry
Journal title
Liebigs Annalen → ACNP
ISSN journal
09473440
Issue
2
Year of publication
1995
Pages
223 - 230
Database
ISI
SICI code
0947-3440(1995):2<223:APBPC>2.0.ZU;2-K
Abstract
alpha,omega-Dialkyl-substituted linear polyenes are synthesized in goo d yields by the palladium-catalyzed coupling reaction of trialkyltin- and iodo-substituted olefinic precursors. Central building blocks are the distannylated butadiene 8 and vinyl iodide 3. Our synthetic strate gy was successfully applied to the preparation of the tert-butyl polye nes 13, 14, and 15 as well as polyenes 25 and 26 with longer alpha, om ega-dialkyl chains.