THE REGULATION OF ENDOCYTOSIS - IDENTIFYING DYNAMINS BINDING PARTNERS

Authors
VALLEE RB OKAMOTO PM
Citation
Rb. Vallee et Pm. Okamoto, THE REGULATION OF ENDOCYTOSIS - IDENTIFYING DYNAMINS BINDING PARTNERS, Trends in cell biology, 5(2), 1995, pp. 43-47
Citations number
47
Categorie Soggetti
Cell Biology
Journal title
Trends in cell biology → ACNP
ISSN journal
09628924
Volume
5
Issue
2
Year of publication
1995
Pages
43 - 47
Database
ISI
SICI code
0962-8924(1995)5:2<43:TROE-I>2.0.ZU;2-W
Abstract
Dynamin is a large GTPase implicated in controlling the initial stages of endocytosis. Its mechanism of action remains uncertain, but it is expected to interact cyclically with components of the endocytic machi nery. Dynamin binds to a number of different macromolecules, including microtubles, SH3-domain-containing proteins, and acidic phospholipids . We interpret these findings in terms of a cooperative interaction be tween dynamin and components of coated and non-coated pits.