Wound complications of the pedal incision continue to compromise succe
ssful limb salvage following aggressive revascularization. Significant
distal wound disruption occurred in 14 of 142 (9.8%) patients undergo
ing pedal bypass with autogenous vein for limb salvage between 1986 an
d 1993. One hundred forty-two pedal bypass procedures were performed f
or rest pain in 66 patients and tissue necrosis in 76. Among the 86 me
n and 56 women, 76% were diabetic and 73% were black. All but eight pa
tients had a history of diabetes and/or tobacco use. Eight wounds were
successfully managed with maintenance of patent grafts from 5 to 57 m
onths. Exposure of a patent graft precipitated amputation in three pat
ients, as did graft occlusion in an additional patient. One graft was
salvaged by revision to the peroneal artery and one was covered by a l
ocal bipedicled flap. Multiple regression analysis identified three fa
ctors associated with wound complications at the pedal incision site:
diabetes mellitus (p = 0.03), age >70 years (p = 0.03), and rest pain
(p = 0.05). Ancillary techniques (''pie-crusting'') to reduce skin ten
sion resulted in no distal wound problems among 15 patients considered
to be at greatest risk for wound breakdown. Attention to technique of
distal graft tunneling, a wound closure that reduces tension, and con
trol of swelling by avoiding dependency on and use of gentle elastic c
ompression assume crucial importance in minimizing pedal wound complic
ations following pedal bypass.