TRACE-ELEMENT DISTRIBUTION IN RAT-BRAIN FOLLOWING LEAD AND LITHIUM SUPPLEMENTATION - A STUDY USING AN EDXRF SPECTROMETER

Authors
SINGH B DHAWAN D CHAND B MANGAL PC TREHAN PN
Citation
B. Singh et al., TRACE-ELEMENT DISTRIBUTION IN RAT-BRAIN FOLLOWING LEAD AND LITHIUM SUPPLEMENTATION - A STUDY USING AN EDXRF SPECTROMETER, Applied radiation and isotopes, 46(1), 1995, pp. 59-64
Citations number
36
Categorie Soggetti
Nuclear Sciences & Tecnology","Radiology,Nuclear Medicine & Medical Imaging
Journal title
Applied radiation and isotopes
ISSN journal
09698043 → ACNP
Volume
46
Issue
1
Year of publication
1995
Pages
59 - 64
Database
ISI
SICI code
0969-8043(1995)46:1<59:TDIRFL>2.0.ZU;2-1
Abstract
Distribution of K, Fe, Cu, Zn, Br and Rb in whole brain samples follow ing combined Pb and Li administration to female Porton rats has been i nvestigated by using the,Energy Dispersive x-Ray Fluorescence (EDXRF) technique. Brain K, Cu and Rb levels are diminished, whereas Fe and Br levels are enhanced significantly following short-term (1 month) and long-term (4 months) combined treatment with Li (1.1 g/kg diet) and tw o doses of Pb (50 and 100 mg/kg body Weight). The Zn levels are lowere d following combined treatment with Li and both the doses of Pb given for short-term only.