SPHENOLOBANE DITERPENOIDS FROM THE LIVERWORT ANASTROPHYLLUM-DONNIANUM

Four new sphenolobane diterpenoids [(3R, 6R*, 9R*, 1OS*)-sphenoloba-1 3E, 16E, 18-trien-4-one, (3R, 6R*, 9R*, 10S*)-18-hydroxysphenoloba-13 E, 16E-dien-4-one (3R, 6R*, 9R*, 10S*)-sphenoloba-13E, 17-dien-4-one, and (6R,9R*,10S*)-3 alpha, 4 alpha-epoxysphenoloba-13(14), 16E-dien- 15, 18-diol] have been isolated from the liverwort Anastrophyllum donn ianum together with two previously known sphenolobanes [(6R, 9R*, 10S )-3 alpha, 4 alpha-epoxysphenoloba-13E, 16E-dien-18-ol and (6R*,9R*,1 0S)-3 alpha, 4 alpha-epoxysphenoloba-13E,17-diene] and four known ses quiterpenoids. Structures were established using spectroscopic methods . H-1 and C-13 NMR data of the new compounds and C-13 data of 3 alpha- acetoxybicyclogermacra-1(10), 4-diene are reported. Copyright (C) 1996 Elsevier Science Ltd