4-HYDROXY-3-NITROSOBENZAMIDE AND ITS FERROUS CHELATE FROM STREPTOMYCES-MURAYAMAENSIS

Authors
CONE MC MELVILLE CR CARNEY JR GORE MP GOULD SJ
Citation
Mc. Cone et al., 4-HYDROXY-3-NITROSOBENZAMIDE AND ITS FERROUS CHELATE FROM STREPTOMYCES-MURAYAMAENSIS, Tetrahedron, 51(11), 1995, pp. 3095-3102
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
51
Issue
11
Year of publication
1995
Pages
3095 - 3102
Database
ISI
SICI code
0040-4020(1995)51:11<3095:4AIFCF>2.0.ZU;2-X
Abstract
Two new colored metabolites of Streptomyces murayamaensis have been is olated and characterized as 4-hydroxy-3-nitrosobenzamide and its ferro us chelate. These structures have been confirmed by synthesis via a mo dified Baudisch reaction. A sample of 3-amino-4-hydroxy[2-H-2]benzoic acid was fed to S. murayamaensis, affording a sample of the 4-hydroxy- 3-nitrosobenzamide ferrous chelate deuterated at C-2 (28.5% enrichment , 3.2% incorporation).