Candida albicans from a patient with dental caries grew on minimal med
ium consisting of agar supplemented with magnesium chloride and sodium
phosphate. Hyphal growth was observed when the yeast was cultured bet
ween 26 degrees C and 28 degrees C under aerobic conditions, and typic
al chlamydospores were formed. However, when the yeast was cultured at
the same temperature under anaerobic conditions, curly hyphae develop
ed on the surface of the medium, but no chlamydospores were formed. Th
is phenomenon was also observed if the culture was started under aerob
ic conditions but was continued under anaerobic conditions.