PLATELET-AGGREGATION INHIBITING AND ANTICOAGULANT EFFECTS OF OLIGOAMINES .28. OLIGOAMINES WITH FLUORESCENT PROPERTIES .C. FLUORESCENT OLIGOAMINES WITH ENHANCED HYDROPHILIC PROPERTIES

Fifteen fluorescent oligoamines with one or two fluorescent groups and two or three basic N-functions were prepared and tested for antiplate let activity (Born-test). Five compounds involving three different flu orophores, i.e. 2-fluorenyl, 1-pyrenyl, and 9-phenanthryl, show an IC5 0 of 7-11 mu mol/L. They are suitable to serve as probes in the field of oligoamine-biopolymere interactions.