Kb. Nolan et Aa. Soudi, SYNTHESIS AND CHARACTERIZATION OF COPPER(II), ZINC(II) AND COBALT(II)COMPLEXES OF SALICYLGLYCINE, A METABOLITE OF ASPIRIN, Inorganica Chimica Acta, 230(1-2), 1995, pp. 209-210
Copper(II), nickel(II) and cobalt(II) complexes of the aspirin metabol
ite salicylglycine (H(2)L), of stoichiometry M(HL)(2) . solvate, have
been prepared and characterised. In these complexes salicylglycinate i
s coordinated to the metal via its carboxylato group and possibly also
its amide oxygen in the copper(II) complex. Under basic conditions co
pper(II) forms the complex Cu(LH(-1)). 2H(2)O . MeOH, in which the lig
and is coordinated to the metal via its carboxylate and phenolate oxyg
en atoms and the deprotonated peptide nitrogen atom.