Bp. Ying et al., STRUCTURE-ACTIVITY-RELATIONSHIPS OF PHYTOTOXIC SESQUITERPENOIDS FROM CANELLA-WINTERANA, Journal of agricultural and food chemistry, 43(3), 1995, pp. 826-829
The structure-activity relationships of 14 drimane sesquiterpenoids is
olated from Canella winterana plus 5 derivatives were examined in a pl
ant growth inhibitory bioassay. It was found that the 11,12-dialdehyde
was the essential moiety and the 9-hydroxy group was not important fo
r activity. The compound with beta-configuration of the 11-aldehyde or
3-acetoxy group showed greater activity than its alpha-isomer.