This article discusses pertinent information regarding general anesthe
sia in potbellied pigs. Because of the increasing popularity of these
animals as house pets, potbellied pigs are being presented for surgica
l procedures, such as ovariohysterectomy, castration, and laceration r
epair, all of which necessitate use of anesthesia. Presurgical conside
rations; preanesthetic medications; and general anesthesia considerati
ons, such as induction, tracheal intubation, maintenance, support and
monitoring, and recovery, are discussed. Potbellied pigs can safely be
anesthetized using the same drugs and techniques used to anesthetize
research or domesticated farm pigs, and inhalation equipment used for
dogs and cats may be used to deliver inhalant anesthetics to pigs weig
hing up to 140 kg. Preanesthetic tranquilization or sedation, as is co
mmonly done in dogs and cats, is difficult to achieve in pigs. Comprom
ised ventilation, including hyperventilation and apnea, may occur duri
ng anesthesia. Malignant hyperthermia syndrome is a possible complicat
ion associated with anesthesia in pigs, although occurrence is rare. T
he unique differences in porcine anatomy that must be taken into accou
nt for the anesthetic process are reviewed. Suggested drugs (preanesth
etic, induction, and maintenance agents) and biochemistry values are l
isted in the tables.