1,3-DIPOLAR CYCLOADDITIONS OF NITRONES TO ALPHA,BETA-UNSATURATED GAMMA-LACTAMS DERIVED FROM (S)-PYROGLUTAMINOL

Authors
LANGLOIS N VANBAC N DAHURON N DELCROIX JM DEYINE A GRIFFARTBRUNET D CHIARONI A RICHE C
Citation
N. Langlois et al., 1,3-DIPOLAR CYCLOADDITIONS OF NITRONES TO ALPHA,BETA-UNSATURATED GAMMA-LACTAMS DERIVED FROM (S)-PYROGLUTAMINOL, Tetrahedron, 51(12), 1995, pp. 3571-3586
Citations number
30
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
51
Issue
12
Year of publication
1995
Pages
3571 - 3586
Database
ISI
SICI code
0040-4020(1995)51:12<3571:1CONTA>2.0.ZU;2-0
Abstract
alpha,beta-Unsaturated gamma-lactams undergo regio- and stereoselectiv e 1,3-dipolar cycloadditions with N-benzyl and N-methyl nitrones and c an act as accepters in conjugate addition of N-methylhydroxylamine. Th ese reactions give access to highly functionalized pyrrolidones.