EPOXIDATION WITH DIOXIRANES DERIVED FROM 2-FLUORO-2-SUBSTITUTED-1-TETRALONES AND 2-FLUORO-2-SUBSTITUTED-1-INDANONES

Authors
BROWN DS MARPLES BA SMITH P WALTON L
Citation
Ds. Brown et al., EPOXIDATION WITH DIOXIRANES DERIVED FROM 2-FLUORO-2-SUBSTITUTED-1-TETRALONES AND 2-FLUORO-2-SUBSTITUTED-1-INDANONES, Tetrahedron, 51(12), 1995, pp. 3587-3606
Citations number
34
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
51
Issue
12
Year of publication
1995
Pages
3587 - 3606
Database
ISI
SICI code
0040-4020(1995)51:12<3587:EWDDF2>2.0.ZU;2-Y
Abstract
Homochiral 2-fluoro-2-substituted-1-tetralones (10a, 10b, 13) and ethy l 2-fluoro-1-indanone-2-carboxylate (16) have been isolated. The dioxi rane derivatives of these ketones have been prepared in situ, and have been shown to epoxidise alkenes but not enantioselectively. The dioxi rane derivative of methyl 2,5,7-trifluoro-1-indanone-2-carboxylate (18 ) has been shown to be comparatively efficient in epoxidation.