EFFECT OF MALATHION ON ENZYMES OF GOAT LIVER AND SERUM

Malathion induced acute toxicity in goat by oral administration was st udied. Malathion administration increased the activity of SGPT, SGOT, alkaline and acid phosphatases whereas AchE activity was decreased, wh ich may be due to modification of active site of AchE. There was no st atistically significant change in liver enzymes except AchE. Histopath ological changes like dilation of sinusoid, hyperamia, cloudy swelling and nacrobiotic changes in hepatocytes were described.