SYNTHESIS AND CONFORMATION OF HEXAHYDRO-ISOQUINO[3,2-A][2]BENZAZEPINES OF THE B-HOMOBERBINE TYPE

Authors
MEISE W ZLOTOS D JANSEN M ZOCHE N
Citation
W. Meise et al., SYNTHESIS AND CONFORMATION OF HEXAHYDRO-ISOQUINO[3,2-A][2]BENZAZEPINES OF THE B-HOMOBERBINE TYPE, Liebigs Annalen, (3), 1995, pp. 567-574
Citations number
23
Categorie Soggetti
Chemistry
Journal title
Liebigs Annalen → ACNP
ISSN journal
09473440
Issue
3
Year of publication
1995
Pages
567 - 574
Database
ISI
SICI code
0947-3440(1995):3<567:SACOH>2.0.ZU;2-A
Abstract
The two-step synthesis of the hexahydro-isoquino[3,2-a][2]-benzazepine s (''B-homoberbines'') 4b-e is described. The main and some further pr oducts of the Bischler-Napieralski reaction of hydroxyamide 3c were is olated and identified. The conformation of the B-homoberbines was inve stigated by X-ray analysis, spectroscopic methods and dehydrogenation with mercury(II) acetate.