We reviewed the electrophysiologic data of 100 consecutive patients wi
th sciatic neuropathy in order to better understand this disorder. Mos
t patients (93%) had electrodiagnostic signs of significant axonal los
s. Seven patients had predominantly signs of demyelination; 6 were due
to compression and 1 was idiopathic. The peroneal division was more s
everely affected than the tibial division in 64% of patients. Tibialis
anterior EMGs were abnormal in 92%, and the EDB CMAP was low in ampli
tude or absent in 80%. CMAP and SNAP amplitudes and EMGs were all norm
al in the tibial division in 12%. In contrast, the tibial division was
more severely affected in only 8 patients. Of those, 5 were due to th
igh trauma (gunshot wounds or femur fracture), 2 from gunshot wounds t
o the hip, and the other was chronic and idiopathic. Sciatic neuropath
ies are commonly, but not always, axonal loss lesions that affect the
peroneal greater than tibial division. (C) 1995 John Wiley and Sons, I
nc.