Iy. Guo et al., PC PROGRAM EXTENDING THE POTTHOFF-ROY LONGITUDINAL DATA-ANALYSIS MODEL TO ALLOW MISSING DATA - KLEINBAUMS METHOD, International journal of bio-medical computing, 38(3), 1995, pp. 243-255
Potthoff and Roy (Biometrika, 51 (1964) 313-326) generalized the multi
variate analysis of variance model into a form that is especially usef
ul for the study of longitudinal growth curve data. Applications of th
is method have, however, been limited by the requirement that each cas
e in the sample be measured at the same set of time points, i.e. there
can be no missing data. In this paper we describe, illustrate, and ma
ke available a user-friendly, interactive PC program implementing Klei
nbaum's (J Mult Anal, 3 (1973) 117-124) extension of the Potthoff-Roy
model to allow incomplete measurement sequences. These missing data ar
e permitted to arise either randomly or by design as in mixed longitud
inal studies.