Estrogen therapy offers women important benefits, including the potent
ial prolongation of life by prevention of coronary heart disease (CHD)
and osteoporotic fractures, and improvement of life by prevention of
menopausal symptoms. Not all women can accept the potential side effec
ts and risks, however which include uterine bleeding, cystic mastitis,
fluid retention, and increased risk of uterine cancer and breast canc
er Thus, the benefits and risks must be patiently weighed for each ind
ividual, and the alternatives of no treatment or other treatment shoul
d be clear We review here the pertinent information that now makes the
se decisions quite sound.